Reporter： Yonggang Ke, PhD
Title： Self-assembly of DNA Nanomaterials and applications
Time： July 4th 09:30am
Inviter：Prof. Wang Qiangbin
Location：Conference Room A718
Biography: Yonggang Ke is an Associate Professor of Biomedical Engineering at Emory University and Georgia Institute of Technology. He received his BSc in Chemistry from Peking University in 1999, and his PhD in Chemistry from Arizona State University in 2009 under the supervision of Prof. Hao Yan. From 2009 to 2014, he was a postdoctoral fellow at Harvard University, working with Prof. William Shih and Prof. Peng Yin. His research primarily focuses on bio-inspired programmable nanomaterials and their applications in biophysics, nanomedicine and materials science, and is supported by the National Science Foundation, National Institute of Health, and Department of Energy. He was a recipient of an NSF CAREER award in 2017 and an NIGMS MIRA award in 2024.
Abstract：Self-assembly of biomolecules can provide solutions to many challenges in our society, including sustainable manufacturing and developing new biomedical technology. DNA nanotechnology has garnered significant attention due to its programmability and precise control of matter at the nanoscale. By combining DNA self-assembly with functional molecules and materials, we can create a rich repository of hybrid nanomaterials and nanomachines, and use them for various applications. In this talk, I will discuss our research in DNA nanotechnology, including fabrication of fully addressable, three-dimensional nanostructures with rationally designed shapes and sizes, creation of dynamic DNA nanomachines that can perform a range of controlled motions at nanoscale. By combining DNA self-assembly with other molecules and materials, we also created an even richer repository of functional nanomaterials and nanomachines, including DNA-guided self-assembly of plasmonic nanoparticles, magnetic nanoparticles, peptides, proteins. Furthermore, we use these DNA-assembly-enabled nanomaterials in a range of biomedical applications, such as DNA-based biosensors, drug delivery systems, and bio-inspired nanodevices.
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