Faculty
Home People Faculty
SHEN He / 沈贺
  • Department：Division of Nanomedicine
  • Position：Associate Professor
  • Expertise：Regenerative medicine; Stem cell
  • Email：hshen2009@sinano.ac.cn
Research Interest
Currently the research mainly focuses on reconstruction of regenerative microenvironment to achieve bone, cartilage and spinal cord repair. We use biomaterials, nanotechnology and stem cells for :
(1) regulating the inflammatory cell to reduce the inflammatory responses
(2) controlled release of exogenous factors and /or preconcentration of factors, and/or 
(3) mimicking the mechanical properties of the native tissue to rebuild the environments for promoting tissue regeneration. 
Experience:

Employment

2018-present   Associate professor

              Suzhou Institute of Nano-tech and Nano-bionics, Chinese Academy of Sciences (CAS) 

2015-2018     Postdoctoral associate in Regenerative medicine   

  Department of Orthopaedic Surgery, University of Pittsburgh, USA      

2014-2018     Postdoctoral associate in Nanomedicine   

              Suzhou Institute of Nano-tech and Nano-bionics, CAS  

 

Education

2009-2014     Ph. D in Cell biology   

              Suzhou Institute of Nano-tech and Nano-bionics, CAS

2005-2009     B.S. in Life science    

              University of Science and Technology of China 
Selected Publication:

 

  1. Ma DZ, Shen H*, Chen FM, Liu WY, Zhao YN, Xiao ZF, Wu XM, Chen B, Lu JN, Shao D, Dai JW*. Inflammatory microenvironment-responsive nanomaterials promote spinal cord injury repair by targeting IRF5. Adv. Healthcare. Mater., 2022, DOI: 10.1002/adhm.202201319 (IF=11.092, Q1)
  2. Shen H#, Fan C#, You Z, Xiao Z, Zhao Y*, Dai J*. Advances in biomaterial-based spinal cord injury repair. Adv. Funct. Mater., 2022, 32(13) 2110628. (IF= 19.924, Q1) (back cover)
  3. Shen H*,#, Xu B#, Yang C, Xue W, You Z, Wu X, Ma D, Shao D, Leong K*, Dai J*. A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury. Biomaterials 2021, 280, 121279. (IF=15.304, Q1)
  4. Ma DZ, Zhao YN, Huang L, Xiao ZF, Chen B, Shi Y, Shen H*, Dai JW*. A novel hydrogel-based treatment for complete transection spinal cord injury repair is driven by microglia/macrophages repopulation. Biomaterials, 2020, 237, 119830. (IF=15.304, Q1)
  5. Shen H#, Wu SY#, Chen X#, Xu B, Ma DZ, Zhao YN, Zhuang Y, Chen B, Hou XL, Li JY, Cao YD, Fu XY, Tan J, Yin W, Li J, Meng L, Shi Y, Xiao ZF*, Jiang XJ*, Dai JW*. Allotransplantation of adult spinal cord tissues after complete transected spinal cord injury: long-term survival and functional recovery in canines. Sci China Life Sci., 2020, 63(12):1879-1886. (IF=10.372, Q1)
  6. Shen H#, Chen X#, Li X#, Jia K, Xiao ZF, Dai JW*. Transplantation of adult spinal cord grafts into spinal cord transected rats improves their locomotor function. Sci China Life Sci., 2019, 62(6), 725-733. (IF=10.372, Q1)
  7. Lin H#, Sohn J#, Shen H#, Langhans MT, Tuan RS*. Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing. Biomaterials, 2019, 203, 96-110. (IF=15.304, Q1)