Faculty
Home People Faculty
WANG Kai / 王凯
  • Department：Division of Nanobiomedicine Research
  • Position：Professor
  • Expertise：Nanomedicine; Organoid; Cell Reprogramming
  • Email：kwang2022@sinano.ac.cn
Research Interest

1.Lipid nanoparticle for high efficiency RNA delivery

 

2. RNA-based cell reprogramming for organoid preparation

 

3.Gene therapy for ocular diseases

Experience:

    Employment 


　　2022 -          Professor      Nanobiomedicine Division, SINANO, CAS 

　  2016 - 2021    Postdoctoral Research Associate/Research Assistant Professor,     UNC Chapel Hill 

　　2015 - 2016      Research Associate       UT El Paso


　　Education 


　　Ph.D. 2014 　 Polymer and Fiber Engineering        Auburn University 

　　B.S.  2010 　 Materials Engineering    Soochow University  
Selected Publication:

 

  1. Kai Wang, Min Zheng, Charles Askew, Xintao Zhang, Chengwen Li, Ashutosh Chikoti, and Zongchao Han, Elastin-like polypeptide facilitated adeno-associated virus transduction with pre-existing immune response, Advanced Therapeutics, doi: 10.1002/adtp.202200128
  2. Kai Wang, Sarah Ahn, Yuhui Chen, Min Zheng, Elisa Landoni, Gianpietro Dotti, Barbara Savoldo, and Zongchao Han GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision, Nature Cancer, 2020, 1, 990–997.
  3. Kai Wang, Min Zheng, Zongchao Han, Light-induced Nrf2-/- mice as atrophic age-related macular degeneration model and treatment with nanoceria laden injectable hydrogel, Scientific Reports, 2019, 9, 14573
  4.  Ruijuan Gao, Rajendra Narayan Mitra, Min Zheng, Kai Wang, Jesse Dahringer, Zongchao Han Developing nanoceria-based pH-dependent cancer-directed drug delivery system for retinoblastoma, Advanced Functional Materials, 2018, 1806248
  5.  Kai Wang, Rajendra Narayan Mitra, Min Zheng, Zongchao Han. Nanoceria-loaded injectable hydrogels for potential age-related macular degeneration treatment, Journal of Biomedical Materials Research Part A, 2018, 106, 2795-2804
  6.  Kai Wang, Zongchao Han. Injectable hydrogels for ophthalmic application, Journal of Controlled Release, 2017 268, 214-224
  7.  Mitra, Rajendra N., Ruijuan Gao, Min Zheng, Ming-Jing Wu, Maxim A. Voinov, Alex I. Smirnov, Tatyana I. Smirnova, Kai Wang, Sai Chavala, and Zongchao Han. Glycol Chitosan Engineered Auto-Regenerative Antioxidant Significantly Attenuates Pathological Damages in Models of Age-Related Macular Degeneration, ACS Nano 2017 11 (5), 4669–4685
  8.  Kai Wang, Krishna C. Nune and Devesh K. Misra. The functional response of alginate-gelatin-nanocrystalline cellulose injectable hydrogels toward delivery of cells and bioactive molecules, Acta Biomaterialia, 2016, 36, 143-151