Sponsored by Suzhou institute of Nano-tech and Nano-bionics (SINANO) and Suzhou industrial park, the 5th Sino-US Nano Forum was held in SINANO June 5-7. Over four hundred scientists from China and US joined to discuss the frontier of nanoscience and nanotechnology including nanomaterials, nano devices, nano-bio interface, energy and environment nanotechnology. This forum enhanced collaboration and exchange among scientists of the two nations, and also provided invaluable opportunities for young researcher and graduated students to communicate with world-renowned scientists.