Speaker:Prof.YU Huazhong,Department of Chemistry, Simon Fraser University, Vancouver, Canada
Time: 4:30p.m.Monday,December 19th
Current guidelines for healthcare emphasize rapid testing and reporting, which can be better satisfied by point-of-care (POC) diagnostic tools rather than centralized medical laboratories using automated multi-analyte analyzers by trained professionals. With POC testing, the turn-around time can be significantly reduced, leading to earlier decision making and more efficient medical treatment. At present, POC protocols are predominantly based on rapid-test immunoassay strips/cassettes that combine gold nanoparticles for colorimetric (mostly qualitative) detection and flow-through systems for sample delivery. Optical disc technology provides a promising alternative to today’s POC testing protocol; we have established both the surface chemistry and signal reading methodology for running bioassays of various molecular analytes on bona fide Blu-ray discs; these bioDiscs can be read quantitatively with standard computer drives or stand-alone disc players, i.e., without any modifications to the hardware and software driver.
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