1. Short strong hydrogen bonds in pharmaceutical crystalline complexes.
2. Similar but different crystal structures.
3, Chiral crystallography.
Employment
|
Professor |
Laboratory of MR Spectroscopy & Imaging, SINANO, CAS | |
|
Jan. 2016-Feb. 2019 |
Assistant Director |
Institute of Nano-device and Nano-material, Jiangsu Industrial Technology Research Institute |
|
Nov. 2010-Mar. 2017 |
Associate Professor |
Laboratory of MR Spectroscopy & Imaging, SINANO, CAS |
|
Oct. 2009-Mar. 2009 |
Visiting Fellow |
"National Sun Yat-sen University", Taiwan |
|
Nov. 2008-Oct. 2010 |
Postdoctoral Research Fellow |
SINANO, CAS&USTC |
|
Jul. 2008-Nov. 2008 |
Assistant Professor |
SINANO, CAS |
Education
|
Ph.D. 2008 |
Radio Physics |
Wuhan Institute of Physics and Mathematics, CAS |
|
M.S. 2004 |
Chemical Engineering |
Wuhan University of Science and Technology |
|
B.S. 2002 |
Chemical Engineering |
Wuhan University of Science and Technology |
1. Xin Chen, Duanxiu Li, Hailu Zhang*, Yanwen Duan, Yong Huang*. Co-amorphous Systems of Sinomenine with Platensimycin or Sulfasalazine: Physical Stability and Excipient-adjusted Release Behavior. Mol. Pharmaceutics 2022, DOI: 10.1021/acs.molpharmaceut.2c00785.
2. Xiaojuan Wang, Qihuang Xie, Di Gao, Xin Ye, Zongwu Deng, Hailu Zhang*. Similarity and Diversity: Cocrystallization of Baricitinib with Four C4-Dicarboxylic Acids. Cryst. Growth Des. 2022, 22, 3218-3227.
3. Xin Chen, Duanxiu Li, Zongwu Deng, Hailu Zhang*. Ketoconazole: Solving the Poor Solubility via Cocrystal Formation with Phenolic Acids. Cryst. Growth Des. 2020, 20, 6973-6982.
4. Xiaojuan Wang, Di Gao, Duanxiu Li, Qihuang Xie, Zongwu Deng, Hailu Zhang*. Collecting the Molecular and Ionization States of Irbesartan in the Solid State. Cryst. Growth Des. 2020, 20, 5664-5669.
5. Ningbo Gong, Yong Zhang, Ying Wang, Hongmei Yu, Baoxi Zhang, Hailu Zhang*, Yang Lu*, Guanhua Du. Versatile Salts as a Strategy to Modify the Biopharmaceutical Properties of Venlafaxine and Potential Hypoglycemic Effect Study. Cryst. Growth Des. 2020, 20, 3131-3139.
6. Yue Yuan, Duanxiu Li, Chenguang Wang, Shaodong Chen, Minmin Kong, Zongwu Deng, Changquan Calvin Sun, Hailu Zhang*. Structural Features of Sulfamethizole and Its Cocrystals: Beauty Within. Cryst. Growth Des. 2019, 19, 7185-7192.
7. Zhijie Zhang, Duanxiu Li, Chun Luo, Chunxiang Huang, Ruchen Qiu, Zongwu Deng, Hailu Zhang*. Cocrystals of Natural Products: Improving the Dissolution Performance of Flavonoids Using Betaine. Cryst. Growth Des. 2019, 19, 3851-3859.
8. Yue Yuan, Lin Wang, Duanxiu Li, Zongwu Deng, Hailu Zhang*. How Many Parameters Can Affect the Solid Form of Cocrystallization Products in Mechanochemical Reactions? A Case Study. Cryst. Growth Des. 2018, 18, 7244-7247.
9. Jianhui Li, Jiaoyang Li, Minmin Kong, Xue Fu, Huaguang Yu, Zongwu Deng, Hailu Zhang*. Quinine Acesulfamates. Cryst. Growth Des. 2017, 17, 58-66.
10. Lin Wang, Min Luo, Jianhui Li, Jianming Wang, Hailu Zhang*, Zongwu Deng. Sweet Theophylline Cocrystal with Two Tautomers of Acesulfame. Cryst. Growth Des. 2015, 15, 2574-2578.
