1. Nano-safety assessment；
2. Environmental toxicity assessment (particulate matters, persistent organic pollutants)；
3. Nanomaterials for diagnostic and therapeutic applications.
Employment
1. Dec. 2012-Present Professor Division of Nanobiomedicine Research, SINANO, CAS
2. May, 2012-Nov, 2012 Associate Research Fellow Taiwan Research Institute (Taiwan)
3. 2011-2012 Postdoctoral Fellow National Chiao-Tung University (Taiwan)
4. 2007-2011 Postdoctoral Fellow National Health Research Institute (Taiwan)
Education
1. B.S. 1996-2000 Department of Environmental Sciences Tunghai University (Taiwan)
2. M.S. 2000-2002 Department of Environmental Engineering National Sun Yat-Sen University (Taiwan)
3. Ph.D. 2002-2007 Department of Environmental Engineering National Chung Hsing University (Taiwan)
1. Yang, M.H., Lin, C.H., Chang, L.W. and Lin, P. (2012) “Application of ICP-MS for the study of disposition and toxicity of metal-based nanomaterials” in Reineke, J. (ed) Nanotoxicity: Methods and Protocols Humana Press Inc, New York, United States.
2. Lin, C.H., Chang, L.W., Wei, Y.H., Wu, S.B., Yang, C.S., Chang, W.H., Chen, Y.C. and Lin, P. (2012) Electronic microscopy evidence for mitochondria as targets for Cd/Se/Te-based Quantum Dot (QD-705) toxicity in vivo. The Kaohsiung Journal of Medical Sciences, 28(10), S53-S62.
3. Yeh, T.K., Chen, J.K., Lin, C.H., Yang, M.H., Yang, C.S., Chou, F.I., Peir, J.J., Chang, W.H., Tsai, M.H., Tsai, H.T., Chang, L.W. and Lin, P. (2012) Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: effects of size and particulate nature. Nanotechnology, 23, 085102.
4. Lin, C.H., Yang, M.H., Chang, L.W., Yang, C.S., Chang, W.H., Wang, C.J. and Lin, P. (2011) Cd/Se/Te-based Cd/Se/Te-based Quantum Dot 705 modulated redox homeostasis with hepatotoxicity in mice. Nanotoxicology, 5, 650-663.
5. Lin, P., Yang, R.H.S., Yang, C.S., Lin, C.H., Chang, L.W. (2010) “Toxicology and Bio-Safety Evaluation of Quantum Dots” in Kumar, C. S. S. R. (ed.) Nanomaterials for the Life Sciences. (vol 6) Semiconductor Nanomaterials. P.429-463. Wiley-VCH Verlag GmbH & Co. KG, Germany.
6. Lin, C.H., Chang, L.W., Chang, H., Yang, M.H., Yang, C.S., Lai, W.H., Chang, W.H. and Lin, P. (2009) The chemical fate of the Cd/Se/Te-based quantum dot 705 in the biological system: toxicity implication. Nanotechnology, 20, 215101.
7. Lin, C.H., Huang, C.L., Chuang, M.C., Wang, Y.J., Chen, D.R., Chen, S.T. and Lin, P.H. (2009) Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells. Toxicology Letters, 188, 11-19.
8. Lin, P.H., Chen, D.R., Wang, T.W., Lin, C.H. and Chuang, M.C. (2009) Investigation of the cumulative tissue doses of naphthoquinones in human serum using protein adducts as biomarker of exposure. Chem. Biol. Interact., 181, 107-114.
9. Lin, P.H., Lin, C.H., Huang, C.C., Fang, J.P. and Chuang, M.C. (2008) 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Modulates the Induction of DNA Strand Breaks and Poly(ADP-ribose) polymerase-1 Activation by 17-Estradiol in Human Breast Carcinoma Cells Through Alteration of CYP1A1 and CYP1B1 Expression. Chem. Res. Toxicol., 21, 1337-1347.
10. Lin, P.H., Lin, C.H., Huang, C.C., Chuang, M.C. and Lin, P. (2007) 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines. Toxicology Letters, 172, 146-58.
11. Lin, C.H., Huang, C.C., Wang, T.W., Wang, Y.J., Lin, P.H. (2007) Disparity in the Induction of Glutathione Depletion, ROS Formation, Poly(ADP-Ribose) Polymerase-1 Activation, and Apoptosis by Quinonoid Derivatives of Naphthalene in Human Cultured Cells. Chem. Biol. Interact., 165, 200-210.
12. Lin, C.H. and Lin, P.H. (2006) Induction of ROS Formation, Poly(ADP-Ribose) Polymerase-1 Activation, and Cell Death by PCB126 and PCB153 in Human T47D and MDA-MB-231 Breast Cancer Cells. Chem. Biol. Interact., 162, 181-194.
13. Lin, P.H., Pan, W.C., Kang, Y.W., Chen, Y.L., Lin, C.H., Lee, M.C., Chou, Y.H. and Nakamura, J. (2005) Effects of Naphthalene Quinonoids on the Induction of Oxidative DNA Damage and Cytotoxicity in Calf Thymus DNA and in Human Cultured Cells. Chem. Res. Toxicol., 18, 1262-1270.
14. Lin, C.H., Leow, H.T., Huang, S.C., Nakamura, J., Swenberg, J.A., and Lin, P.H. (2005) Induction of cytotoxicity, aldehydic DNA lesions, and poly(ADP-ribose) polymerase-1 activation by catechol derivatives of pentachlorophenol in calf thymus DNA and in human breast cancer cells. Chem. Res. Toxicol., 18, 257-264.
15. Lin, P.H., Kuo, Y.L., Wang S.H., Lee, C.M., Shih, H.P., Wu, S.H., Pan, W.C., Kang, Y.W., Cheng, C.C. and Lin, C.H. (2004) Effects of microbial biodegradation on the (anti)estrogenicity of carbaryl and bisphenol-A. J. Engin. Natl. Chung Hsing University, 15(3), 181-196.
16. Hung, C.M., Lou, J.C. and Lin, C.H. (2004) Catalytic Wet Oxidation of Ammonia Solutions: Activity of the Copper-Lanthanum-Cerium Composite Catalyst, J. Environmental Engineering (ASCE), 130, 193-200.
17. Hung, C.M., Lou, J.C. and Lin, C.H. (2003) Removal of ammonia solutions used in catalytic wet oxidation processes. Chemosphere, 52, 989-995.
18. Hung, C.M., Lou, J.C. and Lin, C.H. (2003) Wet Air Oxidation of Aqueous Ammonia Solution Catalyzed by Composite Metal Oxide. Environmental Engineering Science, 20, 547-556.
